New chromosomes remain attached to cell membrane

New chromosomes remain attached to cell membrane


1. The DNA of every eukaryotic cell is stored in one or more CHROMOSOMES located in the NUCLEUS

2. Chromosomes contain most of the cell's DNA which acts as the molecule of heredity.  

3. A duplicated chromosome remains tightly paired with its partner at a region called the CENTROMERE .

4. Before a cell divides, it copies all of its chromosomes. While the two copies of a chromosome are attached they are called SISTER CHROMATIDS.

5. DNA and protein together form a complex called CHROMATIN.


Chromosomes are the structures present in the nucleus of the cells and become visible during stages of cell division. Chromosomes carry genes in linear order. Chromosomes are composed of thin threads of chromatin which in turn is made of DNA and its packing proteins. Condensation of chromatin during cell division makes the chromosomes visible.

DNA is a nucleic acid and serves to store genetic information. Stretch of DNA that codes for a specific protein is called a gene. Genes regulate the genetic traits of organisms.

DNA replication occurs during the S phase of the cell cycle. The replicated DNA is accommodated in sister chromatids of chromosomes. Before the S phase, each chromosome has one chromatid and after the S phase, each of the chromosomes has two sister chromatids that are held together at the centromere. Therefore, each of the two identical halves of a duplicated chromosome is called sister chromatid.

1. Yes

2. Yes

3. No


1. The cell will elongate during the process of mitosis as the drug inhibits the binding of the motor proteins to the kinetochore but not the process of elongation therefore yes is correct.

2. The kinetochore is the proteins which attach to the centromere position to which the microtubules attach, the kinetochore help in the movement of the chromosomes towards the opposite poles but the separation of the chromatids does not involve motor proteins and they will separate.

3. Since the chromosome movement requires the motor proteins therefore the chromosomes will not move towards the opposite poles and therefore no is correct.

The correct answer is "yes, yes, no" or "B, B, A".


In the hypothetical situation stated in the question, an inhibitor blocks the function of the motor proteins in the kinetochore, but allows the kinetochore to remain attached to the spindle. The animal cells treated with this inhibitor would be able to elongate during mitosis, their sister chromatids would separate from each other but the chromosomes would not move to the poles of the cell. The inhibitor only action is to block the function of the motor proteins, and since the motor protein function is to move the chromosomes to the poles of the cells, this will be the only activity that will be affected during cell's mitosis.





In this case, an inhibitor inhibits the activities of the motor proteins in the kinetochore, but permits the kinetochore to bind to the spindle. This inhibitor combines with the animal cells causing cell elongation during mitosis, followed by separation of its sister chromatids without the chromosomes moving to the cell poles.

The inhibitor mainly inhibits the activities of the motor proteins, inhibiting the movement of chromosomes to the poles of the cells during cell's mitosis.

A. Chromatids remain attached to one another until anaphase. 
I believe that centrosome is a the microtubule organizing center for the mitotic spindle. Centrosome acts as the main microtubule-nucleating organelle in animal cells and plays a critical role in mitotic spindle orientation and in genome stability. They are made from two centrioles which are microtubules rings. In addition the centrosome pull chromatids apart during cell division.
To complete the question; The inhibitor has no effect on any other mitotic process, including the function of the nonkinetochore microtubules.
Answer yes or no to the following questions concerning this animal cell that has been treated with the inhibitor;
1. Will this cell elongate during mitosis? The answer is Yes. 
The cell will elongate because the function of these micro proteins will not affect the elongation of the cell during cell division. Thus the elongation of the cell would still take place.

2. Will the sister chromatid separate from each other? The answer is Yes
Separation of sister chromatid during anaphase is independent of the function of the microproteins that have been inhibited and thus it would take place.

3. Will the chromosomes move to the poles of the cell? The answer is No
The chromosomes wont move to the poles as this is the function of the microproteins that have been inhibited, and since inhibition impairs their functioning, movement of the chromosomes to the pole wont take place.

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