19) Which of the following is one of the technical reasons why gene therapy is problematic? A) Transferred genes may insert in an area of critical function. B) Cells with transferred genes are unlikely to replicate. C) mRNA from transferred genes cannot be translated. D) Most cells with an engineered gene do not produce gene product.
AnswerAnswer 19. A) Transferred genes may insert in an area of critical function Gene therapy is used to treat diseases like AIDS, cancer, hemophilia, diabetes and cystic fibrosis by removing faulty genes and adding new genes using viruses as vectors. Sometimes new genes may be inserted in wrong region of DNA and may cause risk of tumour formation. Also some additional cells may be targeted rather than mutated cells and this may lead to cancer formation or other diseases.
I hope this will help you if you like it then give me a thumbs up, thank you!